Artron COVID-19 Test is an antigen-capture immunochromatographic assay, that detects the presence of SARS-CoV-2 nucleocapsid protein in nasal swab specimens. SARS-CoV-2 specific antibody and a control antibody are immobilized onto a membrane support as two distinct lines-Test lines (T) and Control line(C) and combined with colloidal gold-monoclonal antibody against SARS-CoV-2 antigen deposited on the conjugate pad to construct a test strip. When the swab sample migrates in the test strip, SARS-CoV-2 nucleocapsid protein binds to anti-SARS-CoV-2 nucleocapsid protein antibody-gold conjugate, forming an immune complex. The immune complex is then captured by the test line on the nitrocellulose membrane as it migrates through the strip, forming a visible pink or purple line, indicating a positive result. If SARS-CoV-2 is absent in the, sample, no pink or purple line will appear in the test line, indicating a negative result.
To serve as an internal process control, a control band has been designed. This control line should always be seen after the test is completed. The absence of a control line in the control region is an indication of an invalid result.