What Level of Albumin indicates Kidney Failure?

Kidney health is a crucial aspect of overall well-being, and early detection of any abnormalities can help prevent serious complications, such as kidney failure. Albumin, a protein found in the blood, is an essential indicator of kidney function. The presence of albumin in urine, known as albuminuria, can be an early sign of kidney damage [2]. In this context, understanding what albumin is and how it relates to kidney function is crucial for maintaining good health.

What Level of Albumin indicates Kidney Failure?

The most common way to measure albumin in the urine is by using the albumin-to-creatinine ratio (ACR) test [1]. This test compares the amount of albumin to the amount of creatinine and can be done on a spot urine sample or a first-morning urine sample [1].

According to the National Kidney Foundation, a common ACR is less than 30 mg/g [2]. Anything above 30 mg/g may indicate a higher risk of kidney failure or cardiovascular events [2]. It’s important to note that an Albumin-to-Creatinine Ratio (ACR) of 300 mg/g or higher indicates an increased risk of developing kidney and heart issues [2]. This health concern should not be ignored, so prompt medical attention is vital in managing the condition.

What causes albuminuria?

Albuminuria is caused by kidney damage; when that happens, they cannot prevent albumin from escaping into the urine. Many factors can induce or worsen kidney damage, such as:

  • Diabetes: It is estimated that approximately 1 out of every 3 adults living with diabetes suffers from kidney disease [3]. The reason behind this correlation is that elevated glucose levels in the blood can cause harm to the kidneys’ blood vessels [3].
  • High blood pressure: Blood pressure is the force of blood against artery walls. When the blood pressure is too high, it puts an excessive strain on the heart, which can lead to serious medical conditions such as stroke, heart attack, and kidney disease [3].
  • Genetic kidney diseases: Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most frequently inherited disease [4]. In the United States, approximately 1 in 800 people have ADPKD, making it the fourth leading cause of kidney failure [4].

How can albuminuria and kidney failure be prevented and treated?

It is important to address the underlying causes and risk factors that damage the kidneys to prevent and treat microalbuminuria. Some helpful strategies include achieving target blood sugar and blood pressure ranges [4]. Losing weight through lifestyle changes and taking proper medication can also effectively treat albuminuria and reduce the risk of complications [4]. It is advisable to discuss your prevention or treatment plan with your doctor for more details.

Artron’s Microalbuminuria Semi-Quantitative Test for monitoring albuminuria in patients

One of the tests that can be used to monitor albuminuria is Artron’s Microalbuminuria Semi-Quantitative Test, a reliable and easy-to-use test with a high sensitivity of 94.3% and a specificity of 98.3%. The test can be used by healthcare professionals to screen for albuminuria in patients with diabetes, hypertension, obesity, or genetic kidney diseases and to monitor their kidney health and treatment response. If you have any questions about our tests, email us at info@artronlab.com.

 

References

[1] Microalbumin creatinine ratio. (n.d.). https://medlineplus.gov/lab-tests/microalbumin-creatinine-ratio/

[2] Urine albumin-creatinine ratio (uACR). (2023, May 23). National Kidney Foundation. https://www.kidney.org/atoz/content/uacr

[3] Diabetic kidney disease. (2023, June 7). National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/diabetes/overview/preventing-problems/diabetic-kidney-disease

[4] Inherited kidney diseases. (2023, September 25). National Kidney Foundation. https://www.kidney.org/atoz/content/inherited-kidney-disease

Leave a Comment

Your email address will not be published. Required fields are marked *

Scroll to Top